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Frontiers of Medicine 2021, Volume 15, Issue 3, Pages 416-437 doi: 10.1007/s11684-021-0852-7
Keywords: ventricular hypertrophy and fibrosis myocardial force-velocity relationship His-Purkinje pacing renin-angiotensin system inhibitors coronary access impairment
Frontiers of Medicine 2022, Volume 16, Issue 1, Pages 102-110 doi: 10.1007/s11684-021-0850-9
Keywords: COVID-19 RAS inhibitor hypertension all-cause mortality
Jiuyang Xu, Chaolin Huang, Guohui Fan, Zhibo Liu, Lianhan Shang, Fei Zhou, Yeming Wang, Jiapei Yu, Luning Yang, Ke Xie, Zhisheng Huang, Lixue Huang, Xiaoying Gu, Hui Li, Yi Zhang, Yimin Wang, Frederick G. Hayden, Peter W. Horby, Bin Cao, Chen Wang
Frontiers of Medicine 2020, Volume 14, Issue 5, Pages 601-612 doi: 10.1007/s11684-020-0800-y
Keywords: COVID-19 SARS-CoV-2 hypertension angiotensin-converting enzyme inhibitor angiotensin II receptor blocker
Influence of β-elemene on the secretion of angiotensin II and expression of AT1R in hepatic stellate
Ling YANG, Rui ZHU, Qingjing ZHU, Dan DAN, Jin YE, Keshu XU, Xiaohua HOU
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 36-40 doi: 10.1007/s11684-009-0020-y
Keywords: liver cirrhosis beta-elemene hepatic stellate cells angiotensin II receptor angiotensin type 1
ZHANG Huilan, WANG Daowen
Frontiers of Medicine 2008, Volume 2, Issue 1, Pages 11-14 doi: 10.1007/s11684-008-0003-4
ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen
Frontiers of Medicine 2008, Volume 2, Issue 1, Pages 19-24 doi: 10.1007/s11684-008-0005-2
Keywords: therapy Sprague administration cardiac hypertrophy valsartan
Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-
Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG
Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4, Pages 433-444 doi: 10.1007/s11705-014-1454-6
Keywords: Alzheimer’s disease amyloid β-protein peptide inhibitors protein-protein interaction molecular
Abbas TEIMOURI, Nasrin SOLTANI, Alireza Najafi CHERMAHINI
Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 1, Pages 43-50 doi: 10.1007/s11705-010-0532-7
Keywords: corrosion inhibitors mild steel acidic medium theoretical studies DFT
Mitogen-activated protein kinase pathway inhibitors: inhibitors for diseases?
Xu WANG MS, Xiao-Wei GONG MD, PhD, Yong JIANG MD, PhD, Yu-Hua LI PhD,
Frontiers of Medicine 2010, Volume 4, Issue 1, Pages 46-53 doi: 10.1007/s11684-010-0010-0
Keywords: mitogen-activated protein kinase drug target inhibitor signal transduction disease
Zhen Xiang, Yingyan Yu
Frontiers of Medicine 2019, Volume 13, Issue 1, Pages 24-31 doi: 10.1007/s11684-019-0679-7
Keywords: immune checkpoint blockade sensitivity resistance data mining
Analysis of interactions of immune checkpoint inhibitors with antibiotics in cancer therapy
Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 307-321 doi: 10.1007/s11684-022-0927-0
Keywords: tumor immunotherapy immune checkpoint inhibitor antibiotics gut microbiota drug–drug interaction
Advances in newly developing therapy for chronic hepatitis C virus infection
Paul J. Pockros
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 166-174 doi: 10.1007/s11684-014-0334-2
Chronic hepatitis C virus (HCV) infection afflicts a reported 170 million people worldwide and is often complicated by cirrhosis and hepatocellular carcinoma. Morbidity and mortality are decreased with the successful treatment of chronic HCV infection. Increased understanding of the HCV has allowed further development of new direct-acting antiviral (DAA) agents against the HCV and has also allowed the development of IFN-free oral treatment regimens. In late 2013 the first nucleotide polymerase inhibitor regimen with RBV alone for genotypes 2/3 and in combination with a 12-week regimen of PEG-IFN+RBV for genotypes 1, 4 was approved for use in the US. A number of promising new DAA regimens which are IFN-free are in phase 3 development and the first will likely be approved for use in the US in 2014. The currently approved regimens are discussed in detail and currently available data on future regimens are reviewed herein.
Keywords: direct-acting antiviral (DAA) nucleotide polymerase inhibitors protease inhibitors
Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1, Pages 133-145 doi: 10.15302/J-FASE-2021401
Keywords: herbicide / HPPD / inhibitor / quinoxaline / triketon
Monitoring checkpoint inhibitors: predictive biomarkers in immunotherapy
Min Zhang, Jingwen Yang, Wenjing Hua, Zhong Li, Zenghui Xu, Qijun Qian
Frontiers of Medicine 2019, Volume 13, Issue 1, Pages 32-44 doi: 10.1007/s11684-018-0678-0
Keywords: immune checkpoint companion diagnosis PD-L1 tumor mutation burden immune score
Xiaohuan Wang, Peng Zou, Fan Wu, Lu Lu, Shibo Jiang
Frontiers of Medicine 2017, Volume 11, Issue 4, Pages 449-461 doi: 10.1007/s11684-017-0589-5
Keywords: emerging and re-emerging viruses small-molecule inhibitor coronavirus Ebola virus Zika virus life cycle
Title Author Date Type Operation
Challenges and opportunities in improving left ventricular remodelling and clinical outcome following surgical and trans-catheter aortic valve replacement
Journal Article
Renin--angiotensin system inhibitor is associated with the reduced risk of all-cause mortality in COVID
Journal Article
Use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in context of COVID
Jiuyang Xu, Chaolin Huang, Guohui Fan, Zhibo Liu, Lianhan Shang, Fei Zhou, Yeming Wang, Jiapei Yu, Luning Yang, Ke Xie, Zhisheng Huang, Lixue Huang, Xiaoying Gu, Hui Li, Yi Zhang, Yimin Wang, Frederick G. Hayden, Peter W. Horby, Bin Cao, Chen Wang
Journal Article
Influence of β-elemene on the secretion of angiotensin II and expression of AT1R in hepatic stellate
Ling YANG, Rui ZHU, Qingjing ZHU, Dan DAN, Jin YE, Keshu XU, Xiaohua HOU
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Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism
ZHANG Huilan, WANG Daowen
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Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy
ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen
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Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-
Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG
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Synthesis of mono and bis-4-methylpiperidiniummethyl-urea as corrosion inhibitors for steel in acidic
Abbas TEIMOURI, Nasrin SOLTANI, Alireza Najafi CHERMAHINI
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Mitogen-activated protein kinase pathway inhibitors: inhibitors for diseases?
Xu WANG MS, Xiao-Wei GONG MD, PhD, Yong JIANG MD, PhD, Yu-Hua LI PhD,
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Screening responsive or resistant biomarkers of immune checkpoint inhibitors based on online databases
Zhen Xiang, Yingyan Yu
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Analysis of interactions of immune checkpoint inhibitors with antibiotics in cancer therapy
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Advances in newly developing therapy for chronic hepatitis C virus infection
Paul J. Pockros
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DISCOVERY OF TRIKETONE-QUINOXALINE HYBRIDS AS POTENT HPPD INHIBITORS USING STRUCTURE-BASED DRUG DESIGN
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Monitoring checkpoint inhibitors: predictive biomarkers in immunotherapy
Min Zhang, Jingwen Yang, Wenjing Hua, Zhong Li, Zenghui Xu, Qijun Qian
Journal Article